I think I have to go back to the original list to understand the selection of works, because it seems a bit odd to me. Definitely different from most compilations of the "most important sf works" and similar. Some of them I also don't understand exactly why they ended up in the SF/F subset, but definitions of genre boundaries is something you can argue about endlessly. Nevertheless, I like these lists, and I like this one because I have actually read not so few of them: 47 out of 149, that's nearly a third!
So, the ones I have read are in bold, and the ones on my reading list (sort of) are marked with an *asterisk.
- Douglas Adams: The Hitchhiker's Guide to the Galaxy (1979)
 - Brian W Aldiss: Non-Stop (1958)
 - Isaac Asimov: Foundation (1951)
 - Margaret Atwood: The Blind Assassin (2000)
 - *Margaret Atwood: The Handmaid's Tale (1985)
 - Paul Auster: In the Country of Last Things (1987)
 - J.G. Ballard: The Drowned World (1962)
 - J.G. Ballard: Crash (1973)
 - J.G. Ballard: Millennium People (2003)
 - *Iain Banks: The Wasp Factory (1984)
 - Iain M Banks: Consider Phlebas (1987)
 - Clive Barker: Weaveworld (1987)
 - Nicola Barker: Darkmans (2007)
 - Stephen Baxter: The Time Ships (1995)
 - *Greg Bear: Darwin's Radio (1999)
 - William Beckford: Vathek (1786)
 - Alfred Bester: The Stars My Destination (1956)
 - Ray Bradbury: Fahrenheit 451 (1953)
 - Poppy Z Brite: Lost Souls (1992)
 - Charles Brockden Brown: Wieland (1798)
 - Algis Budrys: Rogue Moon (1960)
 - Mikhail Bulgakov: The Master and Margarita (1966)
 - Edward Bulwer-Lytton: The Coming Race (1871)
 - Anthony Burgess: A Clockwork Orange (1960)
 - Anthony Burgess: The End of the World News (1982)
 - Edgar Rice Burroughs: A Princess of Mars (1912)
 - William Burroughs: Naked Lunch (1959)
 - Octavia Butler: Kindred (1979)
 - Samuel Butler: Erewhon (1872)
 - Italo Calvino: The Baron in the Trees (1957)
 - Ramsey Campbell: The Influence (1988)
 - Lewis Carroll: Alice's Adventures in Wonderland (1865)
 - Lewis Carroll: Through the Looking-Glass, and What Alice Found There (1871)
 - Angela Carter: Nights at the Circus (1984)
 - Angela Carter: The Passion of New Eve (1977)
 - Michael Chabon: The Amazing Adventures of Kavalier and Clay (2000)
 - Arthur C Clarke: Childhood's End (1953)
 - GK Chesterton: The Man Who Was Thursday (1908)
 - *Susanna Clarke: Jonathan Strange and Mr Norrell (2004)
 - Michael G Coney: Hello Summer, Goodbye (1975)
 - Douglas Coupland: Girlfriend in a Coma (1998)
 - Mark Danielewski: House of Leaves (2000)
 - Marie Darrieussecq: Pig Tales (1996)
 - Samuel R Delaney: The Einstein Intersection (1967)
 - Philip K Dick: Do Androids Dream of Electric Sheep? (1968)
 - Philip K Dick: The Man in the High Castle (1962)
 - Thomas M Disch: Camp Concentration (1968)
 - Umberto Eco: Foucault's Pendulum (1988)
 - Michel Faber: Under the Skin (2000)
 - John Fowles: The Magus (1966)
 - Neil Gaiman: American Gods (2001)
 - Alan Garner: Red Shift (1973)
 - William Gibson: Neuromancer (1984)
 - Charlotte Perkins Gilman: Herland (1915)
 - William Golding: Lord of the Flies (1954)
 - Joe Haldeman: The Forever War (1974)
 - M John Harrison: Light (2002)
 - Nathaniel Hawthorne: The House of the Seven Gables (1851)
 - Robert A Heinlein: Stranger in a Strange Land (1961)
 - Frank Herbert: Dune (1965)
 - Hermann Hesse: The Glass Bead Game (1943)
 - Russell Hoban: Riddley Walker (1980)
 - James Hogg: The Private Memoirs and Confessions of a Justified Sinner (1824)
 - Michel Houellebecq: Atomised (1998)
 - Aldous Huxley: Brave New World (1932)
 - Kazuo Ishiguro: The Unconsoled (1995)
 - Shirley Jackson: The Haunting of Hill House (1959)
 - Henry James: The Turn of the Screw (1898)
 - PD James: The Children of Men (1992)
 - Richard Jefferies: After London; Or, Wild England (1885)
 - Gwyneth Jones: Bold as Love (2001)
 - Franz Kafka: The Trial (1925)
 - Daniel Keyes: Flowers for Algernon (1966)
 - Stephen King: The Shining (1977)
 - Marghanita Laski: The Victorian Chaise-longue (1953)
 - CS Lewis: The Chronicles of Narnia (1950-56) (Book 1 at least)
 - Joseph Sheridan Le Fanu: Uncle Silas (1864)
 - Stanislaw Lem: Solaris (1961)
 - Ursula K Le Guin: The Earthsea series (1968-1990)
 - Ursula K Le Guin: The Left Hand of Darkness (1969)
 - Doris Lessing: Memoirs of a Survivor (1974)
 - MG Lewis: The Monk (1796)
 - David Lindsay: A Voyage to Arcturus (1920)
 - Ken MacLeod: The Night Sessions (2008)
 - Hilary Mantel: Beyond Black (2005)
 - Michael Marshall Smith: Only Forward (1994)
 - Richard Matheson: I Am Legend (1954)
 - Charles Maturin: Melmoth the Wanderer (1820)
 - Patrick McCabe: The Butcher Boy (1992)
 - Cormac McCarthy: The Road (2006)
 - Jed Mercurio: Ascent (2007)
 - *China Miéville: The Scar (2002)
 - Andrew Miller: Ingenious Pain (1997)
 - Walter M Miller Jr: A Canticle for Leibowitz (1960)
 - David Mitchell: Cloud Atlas (2004)
 - Michael Moorcock: Mother London (1988)
 - William Morris: News From Nowhere (1890)
 - Toni Morrison: Beloved (1987)
 - Haruki Murakami: The Wind-up Bird Chronicle (1995)
 - Vladimir Nabokov: Ada or Ardor (1969)
 - Audrey Niffenegger: The Time Traveler's Wife (2003)
 - Larry Niven: Ringworld (1970)
 - Jeff Noon: Vurt (1993)
 - Flann O'Brien: The Third Policeman (1967)
 - Ben Okri: The Famished Road (1991)
 - George Orwell: Nineteen Eighty-four (1949)
 - Chuck Palahniuk: Fight Club (1996)
 - Thomas Love Peacock: Nightmare Abbey (1818)
 - Mervyn Peake: Titus Groan (1946)
 - Frederik Pohl & CM Kornbluth: The Space Merchants (1953)
 - John Cowper Powys: A Glastonbury Romance (1932)
 - Terry Pratchett: The Discworld series (1983- ) (I have only read the first)
 - *Christopher Priest: The Prestige (1995)
 - Philip Pullman: His Dark Materials (1995-2000)
 - François Rabelais: Gargantua and Pantagruel (1532-34)
 - Ann Radcliffe: The Mysteries of Udolpho (1794)
 - Alastair Reynolds: Revelation Space (2000)
 - Kim Stanley Robinson: The Years of Rice and Salt (2002)
 - JK Rowling: Harry Potter and the Philosopher's Stone (1997)
 - *Geoff Ryman: Air (2005)
 - Salman Rushdie: The Satanic Verses (1988)
 - Joanna Russ: The Female Man (1975)
 - Antoine de Sainte-Exupéry: The Little Prince (1943)
 - José Saramago: Blindness (1995)
 - Will Self: How the Dead Live (2000)
 - Mary Shelley: Frankenstein (1818)
 - Dan Simmons: Hyperion (1989)
 - Olaf Stapledon: Star Maker (1937)
 - Neal Stephenson: Snow Crash (1992)
 - Robert Louis Stevenson: The Strange Case of Doctor Jekyll and Mr Hyde (1886)
 - Bram Stoker: Dracula (1897)
 - Rupert Thomson: The Insult (1996)
 - JRR Tolkien: The Hobbit (1937)
 - JRR Tolkien: The Lord of the Rings (1954-55)
 - Mark Twain: A Connecticut Yankee at King Arthur's Court (1889)
 - Kurt Vonnegut: Sirens of Titan (1959)
 - Horace Walpole: The Castle of Otranto (1764)
 - Robert Walser: Institute Benjamenta (1909)
 - Sylvia Townsend Warner: Lolly Willowes (1926)
 - Sarah Waters: Affinity (1999)
 - HG Wells: The Time Machine (1895)
 - HG Wells: The War of the Worlds (1898)
 - TH White: The Sword in the Stone (1938)
 - Angus Wilson: The Old Men at the Zoo (1961)
 - Gene Wolfe: The Book of the New Sun (1980-83)
 - Virginia Woolf: Orlando (1928)
 - John Wyndham: Day of the Triffids (1951)
 - John Wyndham: The Midwich Cuckoos (1957)
 - Yevgeny Zamyatin: We (1924)
 

